Best Probiotic Supplements (2022) Top Healthy Gut Probiotics to Buy

Probiotic supplements have never been more popular than they are right now. Many individuals take probiotics regularly to support digestion, immunity, energy levels, weight loss, and other benefits.

Good digestion affects virtually every aspect of your health, and good digestion starts with good gut bacteria.

However, not every probiotic supplement is made equal. Some probiotics contain potent doses of probiotics proven to work, whereas others include near-useless bacteria.

Our editorial team is here to help you. We’ve tested hundreds of probiotic supplements, spoken to manufacturers, examined lab reports, and conducted hours of research to discover the best probiotic supplements. Here is what we found.

The Best Probiotic Supplements for 2022

After all of our research, here is how we ranked the very best probiotic supplements for 2022 & beyond:

  • BioFit
  • 1MD Complete Probiotics
  • BioTrust Pro-X10
  • BiOptimizers P3OM
  • Organifi Balance
  • LeanBiome
  • Nucific Bio-X4
  • ActivatedYou Advanced Restorative Probiotic
  • Gundry MD 24 Strain Probiotic
  • Unify Health Labs Multi-GI 5
  • Seed
  • Just Thrive Probiotic
  • VitaPost Probiotic 40-Billion
  • Live Conscious Pro-45
  • Probiotic T-50
  • Nuzena Probiotic 40 Gut Boost +
  • UpWellness Probiotic +
  • Purality Health Micelle Liposomal Probiotic
  • Prime Health Daily Probiotic Balance
  • Oweli Probiotic
  • Earth Echo Probiotic
  • Earth Echo Vitality Bliss Bites
  • Probulin
  • Microbiome Plus
  • FloraSpring (Revival Point)
  • Probiotic America
  • Advanced BioNutritionals Probiotic
  • Simple Promise Ovuna
  • Organixx ProBiotixx
  • PhytAge Labs Replenish 911
  • Vital Plan Advanced Biotic
  • Vital Plan Biome Boost
  • ProBio-Lite
  • Orthobiome

Here’s a summary including ingredients, highlights, and benefits of each of the best probiotic supplements for 2022:



BioFit is one of the leading probiotic supplements that doubles as a weight loss supplement. It also features multiple bonuses to boost your weight loss efforts, including two weight loss recipe books and access to a private members’ area, making BioFit a select option for those looking to support weight loss in various ways.

According to the official website, BioFit has already helped some adults lose 72 pounds since the product was launched. Take BioFit to give your body a healthy dose of healthy probiotic bacteria, then enjoy the weight loss results within just a few days or weeks.

Although it’s safe to be skeptical of the extreme weight loss claims, BioFit is backed by a 180-day money-back guarantee and thousands of positive reviews online. This means you are entitled to a full refund if BioFit’s probiotics don’t help you lose weight. BioFit is currently priced at $59 per bottle, with multiple bottle discounts available.

1MD Complete Probiotics


1MD Complete Probiotics Platinum is a well-rated and popular probiotic with a substantial dose of 51 billion colony forming units (CFUs) per serving, making it one of the most potent probiotic supplements available.

Plus, 1MD claims their probiotic supplement has 11 of the most potent strains of probiotics, allowing you to support digestion, immunity, and more.

1MD also uses a customized mechanism to enhance absorption. 1MD Complete Probiotics uses delayed-release capsules, so the CFUs are not destroyed during digestion. In other words, 1MD Complete Probiotics are easily absorbed by your body, unlike most probiotics. Priced at just $41 per bottle, 1MD Complete Probiotics Platinum is a great-value, high-powered probiotic supplement proven to support digestion, immunity, cognition, and more.

BioTrust Pro-X10


Pro-X10 is one of the most effective probiotics to combat bloating, mood issues, digestive issues, stress, etc. It is manufactured by BioTrust, one of the most trusted names in the supplement space.

By taking BioTrust Pro-X10 daily, you can purportedly use multiple strains of proven probiotic ingredients to support gut health and overall wellness. According to BioTrust, Pro-X10 can help anything from low energy to weight loss to brain fog.

Plus, Pro-X10 is only priced at $34 per bottle, making it one of the better value probiotics on our rankings.

BiOptimizers P3-OM


BiOptimizers P3-OM is a well-rated probiotic supplement that claims to improve your health in virtually every aspect. According to the manufacturer, P3-OM can support mental focus & clarity, sleep quality, energy levels, digestive health, weight loss, lean muscle mass, and overall wellness.

Each capsule of P3-OM contains a strong dose of both probiotic and prebiotic ingredients to support gut health in several different ways. These prebiotic ingredients are designed to help the good bacteria in your gut thrive.

P3-OM is manufactured right here in the United States, and a full 365-day money-back guarantee backs it. It’s been called the best probiotic on the market by some users and remains one of the best premium probiotics for those who want “premium” results. P3-OM is currently priced at $66 per bottle.

Organifi Balance


Organifi Balance is a powdered probiotic supplement that uses USDA-certified organic ingredients to help support your gut health in numerous ways.

Each Balance serving contains 20 billion CFUs and five resilient strains of bacteria to help improve digestion, help with bloating and stomach discomfort, and diversify your gut flora, amongst other benefits.

Organifi is one of the most trusted names in the supplement space. They are entirely transparent – disclosing all of their ingredients, dosages, and probiotic strains upfront, making it very easy to compare their supplement to other formulas. We also like Balance because it contains prebiotics like Jerusalem artichoke, feeding the probiotic strains. Priced at $55 for a 30-day supply, Organifi Balance is one of today’s best probiotic supplements.



LeanBiome is a probiotic supplement made from Lean for Good that claims to help boost your metabolism, destroy hunger cravings, reduce fat storage, and more by diversifying your gut microbiome.

Studies have found that adding some diversity to your gut health can make losing weight easier. In fact, without proper gut health, your body will likely add weight – not lose it.

Each capsule of LeanBiome contains proven probiotic strains like Lactobacillus gasseri, Lactobacillus rhamnosus, Lactobacillus fermentum, and Greenselect Phytosome to help you lose weight and to support gut health. The only real downside to LeanBiome is the price since one bottle is priced at $80. However, if you can afford the cost, LeanBiome is a solid option.

Nucific Bio-X4


Nucific Bio-X4 is a probiotic supplement specifically designed to help you manage your weight. It is backed by a 90-day money-back guarantee and uses four active ingredients to help you boost your metabolism, support your digestion, and defend against cravings. This enables you to attack weight loss in numerous ways.

To help you with these benefits, Bio-X4 uses a blend of proven ingredients like probiotics, prebiotics, green tea extract, and digestive enzymes. It provides you with the ultimate weight loss formula that optimizes your digestion & overall health in a straightforward formula. One bottle of Bio-X4 will cost you $99 with discounts given on multiple bottles.

ActivatedYou Advanced Restorative Probiotic


ActivatedYou Advanced Restorative Probiotic uses 30 different strains of probiotic bacteria to allow you to colonize your gut with billions of healthy bacteria.

According to the manufacturer, the supplement can help improve your energy levels, enhance your mood, balance your body from the inside out, enhance immune function, help your skin and digestive health.

No other probiotic supplement on our rankings comes close to 30 strains. We also like that ActivatedYou discloses all 30 strains upfront, so you know exactly what you are taking. Priced at $70 per bottle, ActivatedYou Advanced Restorative Probiotic is ideal for those looking for a diverse, powerful probiotic supplement with maximum transparency and effectiveness.

Gundry MD 24 Strain Probiotic


Gundry MD 24 Strain Probiotic is another diverse probiotic supplement on our list. As the name would imply, it has 24 unique strains of probiotics to support good digestive health. It is backed by a 4.94-star rating out of 5 and contains a potent dose of 30 billion CFUs per serving.

By taking Gundry MD 24 Strain Probiotic, you can ease gas and bloating, improve digestion, maintain and nourish your gut, improve energy levels, etc.

Gundry MD backs up 24 Strain Probiotic with a 90-day money-back guarantee. Each bottle is currently priced at $65, and the formula is caffeine-free, dairy-free, and vegetarian.

Unify Health Labs Multi-GI 5


Unify Health Labs Multi-GI 5 is a 5-star rated probiotic supplement that uses 12 proven gut boosters to improve gut health dramatically.

According to Unify Health Labs, these 12 ingredients have never been combined before. It was given its name because it claims to provide five specific benefits: improved weight management, improved energy levels, healthier GI lining, better digestion, and improved gut flora. However, there are other benefits as well.

In addition to powerful probiotics, Multi-GI 5 also contains fiber, vitamins, minerals, plants, herbal extracts, and prebiotic ingredients. Priced at $70 per bottle, Multi-GI 5 is ideal for those who want to target digestion in multiple ways from multiple angles.



Seed describes itself as a “daily symbiotic” supplement in minimalistic packaging. Seed features 24 strains of probiotics and prebiotics and is designed to support your overall health while surviving enzymes, acid, moisture, and heat.

Seed is one of the few supplements that put a complete emphasis on science. Seed sees humans as a microcosm of the earth’s ecology, and SeedLabs was founded to develop specialized bacteria to improve biodiversity.

Seed is a high-powered formula that supports whole-body health and gastrointestinal health. According to Seed, their probiotic supplement can help digestion, immune function, gut barrier integrity, cardiovascular health, dermatological health, and nutrient absorption. Best of all, Seed costs just $50 per bottle.

Just Thrive Probiotic


JustThrive Probiotic & Antioxidant blend is a spore-based probiotic supplement. According to Just Thrive, their unique delivery system yields 1000x better survivability than Greek yogurt and other leading probiotics.

Priced at just $50 per bottle, JustThrive Probiotic contains four probiotic strains, including unique strains like HU36 and HU58. There are 3 billion CFUs in one serving of Just Thrive Probiotic.

According to the official website, you can purportedly support digestion, immune health, mood, and more by taking Just Thrive Probiotic daily. Priced at only $50, the formula is paleo, keto-friendly, and vegan.

VitaPost Probiotic 40-Billion


VitaPost Probiotic 40-Billion replenishes your gut flora with potent strains of bacteria. It is designed for immune health, digestive function, energy levels, and overall health and wellness with its’ powerful formula.

According to VitaPost, each strain of bacteria was specifically chosen for its’ specific, targeted benefits and ability to work with other strains. There are only four strains of bacteria in 40-Billion. However, there are 40 billion CFUs in each serving, giving VitaPost one of the most substantial doses of probiotics on our list.

The four strains within VitaPost’s Probiotic 40-Billion include lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus Plantarum, and Lactobacillus paracasei. Each strain works differently to support various aspects of your health. Priced at only $35, VitaPost Probiotic 40-Billion is one of the most affordable options on our list.

Live Conscious Pro-45


Pro-45 from Live Conscious is a powerful probiotic supplement with FOS prebiotics, helping to fuel your probiotic bacteria in several different ways. According to Live Conscious, Pro-45 can support immune health and optimal digestion.

There are 11 robust strains of bacteria in Pro-45 and 45 billion CFUs, making it one of the most potent probiotic supplements on our list. These strains and dosages are clearly labeled upfront for maximum transparency.

Pro-45 is backed by over 1,100+ reviews, with an average star rating of 4.8 stars out of 5. Best of all, despite the transparency, strong dose, and excellent reviews, Pro-45 only costs $30 per bottle, making it a no-brainer.

Probiotic T-50


Zenith Labs Probiotic T-50 is a highly-potent probiotic supplement that supports “a balanced gut bacteria ecosystem.” This may help fight bloating and gas, support immunity, and more.

Probiotic T-50 is one of the only supplements on our rankings that supports memory and enhances cognitive function. Since studies show gut health is essential for cognition, this claim may be legitimate.

Probiotic T-50 is packaged in easy-to-take capsules, and it contains 50 billion CFUs per serving. It is priced at only $49 per bottle, which means it packs a massive punch at a reasonable price.

Nuzena Probiotic 40 Gut Boost +


Nuzena Probiotic 40 Gut Boost + is a popular and well-liked probiotic supplement that provides 40 billion CFUs per serving. Priced at only $35 per bottle, Nuzena Gut Boost + is designed to increase nutrient absorption, reduce bloating, improve digestive health, and much more.

Nuzena 40 Gut Boost + is formulated by health professionals, making it one of the few doctors formulated products on our list. These specific strains of Probiotic Gut Boost 40 + can support your digestion and gut health in several ways, complementing each other to amplify the effects of these probiotic strains.

UpWellness Probiotic +


UpWellness Probiotic + is another popular probiotic product designed to improve digestion, decrease bloating and gas, enhance energy levels and mood, and support fat loss.

By taking UpWellness Probiotic + daily, you can provide your body with six proven & potent strands of beneficial probiotic strains, three adaptogenic superfoods, a daily dose of fiber, and other ingredients to support digestion.

Studies have found gut health isn’t just about using probiotics. You need fiber, prebiotics, digestive enzymes, and other ingredients. UpWellness uses these ingredients in conjunction with probiotics to support gut health in several ways. Priced at just $47 per bottle, UpWellness Probiotic + provides you with everything you need to optimize your gut health, ultimately leading to better overall health.

Purality Health Micelle Liposomal Probiotic


Purity Health Micelle Liposomal Probiotic is one of the most distinctive probiotic supplements in 2022. Purity Health’s probiotic supplement shines because of its micelle liposomal delivery technology and its meticulously designed flagship probiotic bacteria strain, L. Rhamnosus.

This is one of the most researched and beneficial probiotic supplement ingredients available for proper digestive system support and gut health aid. Purality Health (previously PuraThrive) doesn’t stop with a unique formulation of probiotic strains; it also goes above and beyond with its RcME delivery system for optimal absorption and utilization of the beneficial bacteria. When combined with lactoferrin, an iron-binding protein, the micelle liposomal probiotics in Purality Health probiotic supplement can boost bacteria bioavailability to enhance the effects.

Because of its innovative delivery mechanism and high-quality ingredient sourcing techniques, the probiotic supplement comes from one of the most trusted companies today. It has a long history of producing top-quality supplements that genuinely yield results. This low-cost probiotic pill is easily one of the best probiotic supplements today and is priced at $54 for a 30-day supply.

Prime Health Daily Probiotic Balance


Probiotic Balance is a highly advanced gut health supplement that uses DE111 and other powerful ingredients to support immunity, regularity, digestion, and fat burning.

Like many other popular probiotic ingredients on our list, Probiotic Balance is marketed towards those who want to support gut health in several different manners. This specific blend in Probiotic Balance includes lactobacillus rhamnosus, lactobacillus casei, and Lactobacillus Plantarum, among others, to support weight loss, digestion, and many other benefits.

Despite all of these benefits, Probiotic Balance from Prime Health Daily is priced at only $49 per bottle, making it an excellent valued option.

Oweli Probiotic


Oweli Probiotic is a powerful probiotic supplement that contains 40 billion CFUs of bacteria in each serving. This full-spectrum formula contains multiple different strains of bacteria to support immunity, gut wellness, and overall wellness in several ways.

In addition to digestion, Oweli claims their probiotic supplement can support metabolism, skin health, mood, and feelings of well-being, amongst other benefits.

Oweli is also competitively priced at just $30 per bottle, delivering a substantial dose of probiotics without breaking the bank. They also disclose all strains upfront, including Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus Plantarum, Lactobacillus paracasei, with two complementary ingredients (a marine polysaccharide complex and fructooligosaccharides as prebiotics). If you want a solid probiotic without costing a fortune, Oweli is a reliable option.

Earth Echo Probiotic


Earth Echo Probiotic contains a dozen potent strains of probiotic bacteria to enhance gut health, boost immunity, enhance digestion, and reduce bloating, amongst other benefits.

Earth Echo Probiotic also claims to reduce food cravings, helping to balance hunger hormones to make meals more satisfying and enjoyable.

To achieve these benefits, Earth Echo Probiotic contains 12 “super strains” of bacteria, including lactobacillus acidophilus, Bifidobacterium lactis, and Lactobacillus Plantarum, among other strains. Priced at only $35 per bottle, Earth Echo Probiotic is an excellent valued probiotic supplement.

Earth Echo Vitality Bliss Bites


Want a unique way to try probiotics? Perhaps Earth Echo Vitality Bliss Bites may be right for you. These delicious chocolates contain 72% cacao, probiotics, and prebiotic ingredients to support gut health.

Their chocolate is USDA-certified organic and also sourced from fair trade locations. It’s an easy, guilt-free way to support gut health without having messy powders, capsules, or tablets found in other probiotics.

Earth Echo uses coconut sugar and organic agave inulin to sweeten its chocolates. As with all Earth Echo products, the emphasis is on natural ingredients for better gut health and overall wellness. One box starts at $50 and is perfect if you’re looking for a tasty, unique way to try probiotics.



Probulin is a probiotic product described as “the next generation of probiotics.” It comprises several different products available to address several \health concerns, and Probulin aims to capitalize on the rapidly expanding probiotic industry.

Many probiotic supplements claim to support colon and kidney health, whereas others are designed for immunity or energy levels. Some Probulin supplements are even built for digestion and overall wellness.

Probulin is one of the few supplements available in both stores or online. It is well regarded in the supplement industry and is prized for its’ diverse range of probiotic products and specialized formulas. A 45-day money-back guarantee backs every order of Probulin, and they start at only $20.

Microbiome Plus


Microbiome Plus is a powerful probiotic product that claims to support immune health & digestion using a wide range of bacteria strains, supplements, and products.

The company’s flagship formula uses a particular type of bacteria named L. Reuteri NCIMB 30242. It is clinically proven for effectiveness, and in one study, it was found to lower LDL cholesterol by 11.64% and increase vitamin D levels by 25.5%. It also improved overall gastrointestinal health.

Suppose you’re looking for an affordable, high-powered probiotic supplement or a blend of both probiotics and prebiotics. In that case, Microbiome Plus may be exactly what you need to support your gut health. Microbiome Plus currently starts at only $25 per bottle.

Revival Point FloraSpring


Revival Point FloraSpring is a probiotic supplement that supports digestion, improves metabolism, and reduces food cravings, making it easier to lose weight.

Under normal circumstances, when you eat foods, you absorb most of the calories of the food you eat. However, If you take FloraSpring, your body only absorbs a portion of your calories, converting the rest to energy. This may help you lose weight more efficiently.

Some of the other benefits of FloraSpring include improved energy levels and focus, reduced cravings for food, and metabolism support, amongst other benefits. One bottle of FloraSpring starts at $50.

Probiotic America


Probiotic America Perfect Biotics is a probiotic formula designed by Dr. Cary Nelson to optimize your gut health in several ways. It uses several probiotic strains to supply you with 30 billion CFUs in each serving.

Probiotic America constantly researches and develops new combinations of bacteria to develop the latest and greatest probiotic supplements. It was founded to improve the health and lives of all people living on Earth.

Taking Perfect Biotics can support gut health, immunity, digestion, energy levels, cognitive health, etc. Probiotic America starts at $70 and is third-party tested for accuracy and dosage. It’s also backed by thousands of satisfied reviews from individuals worldwide.

Advanced BioNutritionals Probiotic


Advanced BioNutritionals Probiotic Formula is a top-rated probiotic listed at just $20 per bottle, making it one of the most affordable products on our list.

This ultra-high potency formula contains four individual strains of bacteria to support cognition, digestion, memory, and overall wellness. These four strains of bacteria include Lactobacillus acidophilus, Bifidobacterium lactis, Bifidobacterium bifidum, and Bifidobacterium longum.

Each serving contains 15 billion colony forming units across all four strains and prebiotic ingredients to help these good bacteria strive. If you’re looking for a potent probiotic that’s affordable and backed by thousands of satisfied customer reviews, Advanced BioNutritionals may be right for you.

Simple Promise Ovuna


Ovuna is a probiotic supplement from Simple Promise that is designed to relieve symptoms of menopause, aid overall gut health, and supports healthy weight management. While many other probiotic ingredients target weight loss and digestion only, Ovuna is one of the few probiotic supplements designed to relieve symptoms of menopause.

Ovuna also has unique ingredients we don’t often see in other probiotic supplements such as moringa oleifera, curry leaf, turmeric, and different rare strains of bacteria. Each serving contains 15 billion CFUs, providing you with a high dose of healthy bacteria for gut health.

One bottle of Ovuna is priced at $49 per bottle and comes with an industry-leading 365-day money-back guarantee.

Organixx ProBiotixx


Organixx ProBiotixx is a powerful formula that claims to eliminate common digestive issues like constipation and bloating rapidly. However, by taking ProBiotixx daily, Organixx claims you can also experience better mental focus & energy levels, relieve bloating, higher energy levels, and weight loss.

Each capsule of ProBiotixx contains 2.5 billion CFUs of a single strain of bacteria – named Lactobacillus Plantarum, one of the most popular probiotic strains.

While we would prefer a diverse group of bacteria, Organixx ProBiotixx is one of the top-rated probiotic supplements. Backed by thousands of reviews, ProBiotixx starts at $45, with discounts given on multiple bottle orders.

PhytAge Labs Replenish 911


PhytAge Labs Replenish 911 is a high-powered probiotic formula with ten probiotic strains to support gut health in several ways. In fact, according to PhytAge Labs, just one of the strains found in Replenish 911 can help you lose between 10 to 34lbs of weight in just four weeks.

Dramatic weight loss claims aside, Replenish 911 can also supposedly help control inflammation, boost immunity, and eliminate common digestive issues like bloating and gas.

Although we are skeptical of some of the claims made by PhytAge Labs, it continues to be one of the more popular gut health supplements on the market. One bottle starts at $69, with discounts on several bottle orders.

Vital Plan Advanced Biotic


Vital Plan Advanced Biotic claims to promote microbiome balance and provides secondary support for gut flora. Created by Dr. Bill Rawls, MD, Advanced Biotic contains six powerful herbs to support immune function and gut health.

Technically, Advanced Biotic doesn’t contain any probiotics. Instead, it includes berberine, cat’s claw extract, garlic, sarsaparilla, Japanese knotweed extract, and others. Instead of delivering bacteria, these ingredients are designed to support the existing bacteria already within your gut.

Vital Plan Advanced Biotic is priced at $58 and is backed by a 90-day money-back guarantee. It remains one of the best supplements for digestive health and is one of the few products on our list recommended and formulated by a doctor.

Vital Plan Biome Boost


Biome Boost is the second probiotic supplement from Vital Plan on our list. Like Advanced Biotic, Biome Boost was developed by Dr. Bill Rawls, MD. It was explicitly designed to support overall gut health for better wellness.

Biome Boost is one of the unique supplements available in a liquid tincture instead of a capsule or powder. Take two droppers of Biome Boost by itself or mix it with a glass of water.

Each serving of Biome Boost contains 1,920mg of ingredients like neem leaf extract, southern prickly ash bark extract, Chinese salvia root extract, and several other natural ingredients. Together, these ingredients work in several ways to support gut health, immunity, and more. Biome Boost starts at $59 and is backed by a 90-day money-back guarantee.



Golden After 50 ProBio-Lite is the only probiotic supplement on our list specifically geared towards adults over 15.

According to Golden After 50, your body needs different nutrients once you get older. With ProBio-Lite, you get 5 billion CFUs of probiotic bacteria to help reduce heartburn, support digestion, immunity, etc.

Some proven probiotic ingredients include Lactobacillus acidophilus, Lactobacillus salivarius, Lactobacillus Plantarum, and Bifidobacterium lactis. One bottle of ProBio-Lite costs $69, with multiple bottle discounts available. If you’re over 50 and looking for a probiotic, then ProBio-Lite may be right for you.



Orthobiome is a doctor-formulated and recommended product created by a company known as the Healthy Living Association.

It features 20 billion CFUs across nine individual probiotic strains. Orthobiome is a straightforward, no-nonsense, high-powered probiotic that promises to eliminate bloating and gas, mental fog, mood swings, weight gain, etc.

In addition to supporting gut health, Orthobiome can help you lose weight by reducing food cravings, making it easier for you to manage your weight. It can also enhance appetite control, accelerating fat loss. At only $30 per bottle, Orthobiome is an excellent, non-nonsense option and provides excellent value for the price.

How We Ranked the Best Probiotic Supplements

Although every probiotic supplement claims to be the best probiotic on the market, we know this simply isn’t true. Once you look beneath the surface, you can quickly see significant differences between probiotic supplements on the market.

We separated the very best from the worst probiotics available today:

Colony Forming Units (CFUs)

The more colony-forming units, or CFUS, a probiotic possesses, the more living cultures it uses to support your digestive tract. However, a more significant number of CFUs does not necessarily mean a better probiotic supplement. However, it is still one of several indicators we used to rank the very best probiotic supplements today.

Diversity and Quality of Strains

There are dozens of powerful probiotics known to support gut health. Each strain has its own set of potential benefits as well. Multiple strains of high-quality probiotics are included in the best probiotic supplements to balance gut health. You want as many strains of high-quality probiotics as possible to maximize digestion & overall health.

Manufacturer Reputation & Transparency

Some supplement companies have produced high-quality probiotics for over a decade, giving them a leg up on the competition. Others are new to the sector, introducing formulas in response to current trends. We weren’t anti-startup, but we did prefer manufacturers with solid transparency and a proven history of producing quality supplements.

Delivery System

Enteric coatings are used on some probiotics to shield the active components from stomach acid. Probiotic supplements are made out of living microorganisms. If you don’t take the proper capsule, your stomach acid will kill the healthy bacteria before they reach your digestive tract, essentially being worthless. As a result, a smaller probiotic with a suitable delivery mechanism can be preferable to a bigger probiotic with a lousy delivery system.

Complementary Ingredients

Studies have proven probiotics are essential for gut health. However, like anything, they need fuel to survive and to thrive. Prebiotics are a special kind of fiber that good bacteria feed on, improving the health of your gut. We preferred probiotic supplements that utilized these types of ingredients and digestive enzymes or other complementary ingredients.

Formulated by Doctors, Nutritionists, or Other Professionals

The best probiotic supplements are formulated and recommended by medical doctors, PhDs, registered dietitians, or nutritionists. We tried to avoid probiotic supplements manufactured by marketing teams with no medical backing.

Honest Advertised Benefits

Some probiotic supplement businesses engage in deceptive marketing, claiming that their supplements may help you lose 30 pounds in a month without diet or exercise, treat gastrointestinal disorders, and solve other health issues. We were skeptical of probiotic supplement firms that made false claims about weight loss or other potential benefits of their product.

Money-back & Satisfaction Guarantee

Gut health supplements may or may not be effective for you. Sometimes, they simply fail to deliver the intended benefits for whatever reason. We preferred gut health products that offered a money-back or satisfaction guarantee. Most of the top-ranked probiotics, for example, gave a 60- to 90-day money-back guarantee, with several offering 365-day guarantees. If you don’t experience results, you should get your money back.

Overall Price & Value

A probiotic supplement does not have to be expensive to be high quality. There are plenty of high-quality probiotics in the $20 to $50 range. Some businesses charge a premium for high-quality ingredients, while others do so for no apparent reason. We simply preferred that probiotics provided you with the best value, no matter their price.

Customer Reviews

The best way to get an idea of the average customer experience is to read genuine customer reviews. We examined thousands of customer reviews to learn what they thought of the product. Did they experience benefits? Were there side effects? Would they recommend it to their friends or family? The better the overall customer experience was, the higher we ranked the product.

What are Probiotics?

Probiotics are “good” or beneficial bacteria that reside in your digestive tract.

Believe it or not, your body contains 10x the number of bacteria cells as it does human cells. These bacteria are responsible for a variety of crucial functions throughout the body.

In recent years, probiotic supplements have become very trendy. However, their use goes back centuries. Probiotic beverages have been popular in Japan for centuries. Northern Europeans used to consume probiotics in the form of a diet rich in fermented foods – such as yogurt.

Growing research has connected probiotics to several benefits, so they’ve surged in popularity since the mid-1990s.

Your bowel is home to 100 trillion microorganisms across over 500 different strains of bacteria. By complementing these bacteria colonies with a probiotic supplement, you may enjoy several health benefits.

Benefits of Probiotics

Believe it or not, probiotics have plenty of health benefits. According to Harvard Health and other leading health experts, probiotic supplements deliver the following benefits:

Eliminates or Relieves Irritable Bowel Syndrome

Probiotics may be able to aid you if you have irritable bowel syndrome. After taking a probiotic, many individuals claim to have reduced symptoms of irritable bowel syndrome. It is thought that IBS may be connected to gut inflammation, which probiotics can combat.

Balance Friendly Bacteria in Your Digestive System

Your digestive system breaks down the foods you eat, extracts the nutrients they contain, and plays an integral part in your general health and well-being. You can help balance the friendly bacteria in your gut by taking a probiotic supplement, which plays a vital role in your overall health.

Supports Healthy Inflammation

Your gut may become inflamed due to several reasons. Studies have found inflammation of the gut is directly related to an increased risk of illness. It may also play a role in developing diarrhea, irritable bowel syndrome, and Crohn’s disease. You can help control your risk of illness by taking a probiotic supplement to maintain healthy inflammation in your gut and throughout your body.

Help with Allergies and Eczema

Although you may not expect it, taking a probiotic supplement has helped many people with allergies and eczema. Although studies haven’t been able to replicate this in all persons, some small studies have found a link between probiotics and allergies in children. In one study, researchers discovered that infants given probiotic-supplemented milk had lower eczema rates than those given milk without probiotics. Other research studies have found that pregnant women who take probiotics may pass on superior allergy and eczema defenses to their babies after delivery.

Helps Support Healthy Cholesterol

Believe it or not, the health of your intestines is linked to the health of your heart and blood vessels. Gut health appears to affect cholesterol, preventing some bad cholesterol from being absorbed while allowing good cholesterol to be. In one study, researchers discovered that certain strains of probiotic bacteria lower cholesterol by breaking down bile in the gut, which aids digestion. Other studies found similar results as well.

Fights Diarrhea

A probiotic supplement may be able to aid you if you’re suffering from diarrhea. Probiotics were reported to prevent antibiotic-associated diarrhea by 42 percent in one research study.

Supports Blood Pressure

Some studies have found a direct connection between blood pressure and probiotic use. For example, in one review of nine studies, researchers found probiotics were associated with lower blood pressure levels.

Supports Overall Gut Health & Digestion

One of the probiotics’ primary and apparent benefits is supporting your overall gut health and digestion. A good probiotic supplement supplies your body with beneficial bacteria, supporting gut health.

Weight Loss

Many people use probiotics to help them lose weight. Studies have shown probiotics to increase appetite control by making you feel fuller for longer. According to other research studies, probiotics prevent your body from absorbing excessive amounts of fat, allowing you to absorb fewer calories from your food.

Urological & Vaginal Health

Some women use probiotics for urological and vaginal health. The vaginal ecosystem is a well-balanced environment rich in helpful bacteria. Probiotics can help to maintain a healthy microbiome by complementing these microorganisms. A good probiotic can assist with diseases like bacterial vaginosis, yeast infections, and urinary tract infections by restoring the balance of microorganisms in your urological system and vagina.

Improved Immunity

Your gut contains 80% of your immune system and is responsible for filtering toxins, nourishing your gut lining, and defending your body from potential pathogens. Probiotics, for example, were discovered to help enhance your immune system while also limiting the growth of dangerous gut bacteria in one study. Gut bacteria levels that are high appear to be linked to a lower risk of respiratory infections.

Better Cognition / Elimination of Brain Fog

Many people are astonished to discover that taking a probiotic supplement can potentially relieve their mental fog. Believe it or not, your gut and brain health are intertwined. When your gut flora is out of equilibrium, your brain receives mixed signals. As a result, a decent probiotic supplement can aid cognition, memory, mental fog, and overall brain health.

Side Effects of Probiotics

When healthy adults use regular dosages, probiotics are not associated with significant side effects. According to an NIH review study, probiotics have been proven safe in various studies.

However, it is possible to experience mild gas, abdominal pain, diarrhea, constipation, or bloating – especially during the first few days of using a probiotic supplement. However, most people do not experience any of these symptoms.

Recommended Dosages of Probiotics

Probiotic supplements have different CFUs and strains of bacteria. This means there’s no single “correct” recommended dosage.

However, yogurt must contain at least 1 billion CFUs of probiotic bacteria to be considered probiotic.

Most supplements will contain between 5 billion to 10 billion CFUs. Some more powerful probiotics have 50 billion to 100 billion CFUs per serving.

Do Probiotics Work? – What Science Says

There is plenty of scientific research proving probiotics’ safety and efficacy. Studies have found that probiotic supplements can support digestive health, weight loss, immunity, etc.

In a single review conducted by the National Institutes of Health, researchers found that certain probiotic strains like Lactobacillus, Bifidobacterium, and Saccharomyces boulardii were associated with effects like:

  • Help with colic in infants
  • Support against issues like allergies, asthma, and acne
  • It influences your body’s immunity and enhances immune function
  • Supports gut health for specific digestive problems, like diarrhea, IBS, bowel disease, inflammatory bowel disease, and constipation
  • Produce substances that improve overall digestion for better nutrient absorption
  • Maintains a healthy community of microorganisms
  • It helps replace good bacteria after previously being disturbed (after antibiotic use, excessive alcohol use, or inflammation)

Probiotics impact the entire body, even though they are found in your stomach. For example, your gut houses 80% of your immune system, which affects every part of your body. When you take a probiotic supplement to help your gut health, you help your body’s defenses in various ways.

The findings above were echoed in a Harvard Health assessment of probiotics. According to researchers, probiotic supplements may help treat or prevent diarrhea, irritable bowel syndrome, ulcerative colitis, Crohn’s disease, H. pylori, vaginal infections, urinary tract infections, and other problems.

Harvard researchers discovered, however, that different probiotic strains had significantly diverse impacts. Taking only one probiotic strain will not provide you with all the following benefits. Some strains are more potent than others, while others impact only certain body regions. You can improve your chances of receiving advantages by selecting a decent probiotic supplement.

Probiotics could play a role in medical nutrition therapy, according to a 2004 study. Researchers determined that probiotic supplements could balance bacteria levels in the gut, restoring the natural equilibrium, after evaluating decades of research on probiotic supplements. Everything from immunity to weight reduction to allergy defense relies on a healthy gut balance.

Others use probiotics to help with diarrhea. Researchers examined 35 research papers on diarrhea and probiotics in a review study, indicating that probiotics can lessen the duration of infectious diarrhea by an average of 25 hours. In a comparative trial, probiotics were proven to reduce diarrhea even when it wasn’t caused by a specific sickness or illness, decreasing diarrhea by 42 percent. In another trial, probiotic supplements were found to reduce the risk of diarrhea by 57 percent in children and 26 percent in adults.

According to research, probiotics have also been connected to mental health, cognition, mental fog, and memory. Researchers discovered proof that probiotic supplements can help with anxiety, sadness, OCD, memory, and even autism in an evaluation of 15 trials on probiotic supplements. After taking Bifidobacterium and Lactobacillus strains for 1 to 2 months, participants in these studies had significant cognitive improvement.

Probiotics may be able to help you in losing weight. Probiotics, for example, were found to help people lose weight through numerous processes in one study. Some probiotic strains, for example, make you feel fuller for longer by blocking fat absorption in the intestines. Researchers discovered that consuming low dosages of Lactobacillus gasseri for 12 weeks resulted in an 8.5 percent reduction in abdominal fat in one of the most extensive weight loss studies utilizing probiotics. A total of 210 people took part in the study.

Supplements have not been demonstrated to be beneficial in all probiotic research. Researchers discovered that some patients do not benefit from probiotic supplementation in this 2018 study. You don’t need to take a probiotic to restore your gut health if you already have enough probiotics in your stomach. Many people who eat a well-balanced diet and avoid pollutants in their lives, such as those who don’t use antibiotics, may not require a probiotic supplement.

Overall, the finest probiotic supplements on the market contain strains that have been scientifically proven to help with digestive health in various ways.

Probiotic Supplement FAQs

Our expert team has gotten plenty of questions about probiotics, how they work, if they’re safe, etc. Here are the answers to your most frequently asked questions:

Q. What are probiotics?

A: Probiotics are live bacteria that live in your gut. Studies have found that they have several health benefits.

Q. Who should take probiotics?

A: People can take probiotics for several reasons, such as digestive issues, immunity, weight loss, cognition, etc.

Q. Do I need a probiotic?

A: Some individuals have naturally high levels of probiotic bacteria in their gut. However, many people have imbalanced gut flora, thanks to the modern diet. Antibiotics, unhealthy lifestyles, and frequent alcohol use can also factor into gut flora.

Q. What do probiotics do?

A: Probiotic supplements primarily work to improve or restore gut flora, helping to balance bacteria in your gut. These bacteria help extract nutrients from the foods you eat, break down food, help support your body’s natural digestive processes, and filter out toxins.

Q. When should I take probiotics?

A: You can take probiotics at any time of day. These bacteria help repopulate your digestive tract with healthy bacteria, so, to be honest, the timing doesn’t matter much. However, many supplements recommend taking probiotics 15 to 30 minutes before a meal.

Q. Are probiotics safe?

A: Probiotics are widely considered safe when used by healthy adults in regular doses. There is little objective evidence that there are any side effects when taking probiotics.

Q. Can I lose weight with probiotics?

A: Probiotics have been shown to aid in weight loss in some individuals. If you are struggling to lose weight, then a probiotic may be able to help.

Q. Will probiotics cause gas?

A: Some people experience bloating or gas within the first few days of taking probiotics. However, you should not experience any significant gassiness beyond the first few days of use.

Q. Will probiotics cause constipation?

A: Like gas, probiotics should not cause constipation on their own. If you experience constipation, it’s likely a sign you need to drink more water or eat more fiber.

Q. What are the best foods for probiotics?

A: Some of the best foods for probiotics include kefir, kombucha, sauerkraut, pickles, sourdough, cheeses, and other fermented foods.

Q. Will probiotics make me poop?

A: Probiotics may increase the frequency of bowel movements by supporting overall digestive health. If you feel that you might be blocked up or struggling to maintain digestive regularity, then a probiotic supplement may help.

Q. Are probiotic supplements good for you?

A: Probiotic supplements appear to support digestive health, immunity, and other areas of your health. Many of these benefits have been confirmed in placebo-controlled, double-blind studies.

Q. How long does it take for probiotics to work?

A: Probiotics tend to work best over two or three weeks. It takes time to replenish and restore healthy gut bacteria. If you take probiotic supplements for several months, you can give your gut the absolute best chance to repopulate its gut bacteria.

Q. What’s the difference between prebiotics and probiotics?

A: Probiotics are beneficial bacteria in your body that support digestion, immunity, and more. Prebiotics are ingredients that feed these healthy bacteria. Most prebiotics are different types of fiber, but they can include several components.

Q. Will probiotics help with bloating?

A: Many people who experience bloating take probiotics to relieve their symptoms. Studies have found probiotics might help with bloating by balancing gut bacteria.

Q. What are CFUs in probiotics?

A: CFUs stand for colony-forming units. The more CFUs a probiotic has, the more live cultures will enter your body with every serving. More CFUs do not necessarily mean a probiotic is a better supplement.

Q. How do I take probiotics?

A: Most probiotics come in either capsule or powder form and are designed to efficiently pass through your stomach acid. This means more live bacteria will survive the passage into your digestive tract. However, there are also probiotic beverages, yogurts, and other supplements.

Q. How much should a probiotic cost?

A: A probiotic supplement can range wildly in price, depending on the ingredients. You can expect to spend anywhere from $20 to $100 for a one-month supply.

Q. What are the best probiotics?

A: BioFit, 1MD Complete Probiotics, BioTrust Pro-X10, and BiOptimizers P3OM are just a few of the best probiotic supplements available online today.

The Best Probiotic Supplements for 2022 Final Word

Probiotics are proven, popular ways to support overall gut health, digestion, immunity, etc.

Studies have found gut health can improve immunity, nutrient absorption, allergy defense, cognition, heart health, and many other aspects of your health.

To purchase the best probiotic supplements available today, check out our list of the world’s best probiotic supplements above.

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