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Best Immunity Boosters 2021 Top Immune Enhancing Supplements

The body’s immune system is the most important factor in keeping the body safe. Everyone needs a defense against the pathogens in the world around them, protecting the individual from illness, infections, and diseases.

Anyone that takes care of their immune system will find that they have much better health than if they ignore it. Some people are lucky and find that they have a naturally strong immune system, while others have to work hard to maintain a healthy lifestyle that can improve their immunity with time. Supplements make these improvements rather easy, offering extra vitamin C, zinc, and other necessary nutrients that the body needs to keep up.

While there are many supplement options online today, most of them do not provide users with the nourishment that they need. After plenty of research, this guide will show users the top immunity boosters on the market in 2021.

The Rankings of the Best Immunity Boosters of 2021

After extensively reviewing lab reports, ingredient lists, and more, this guide eventually narrowed down the immunity boosters to the select group below. Each one met the criteria and surpassed the other formulas on the market today.

Read on to learn about each of these formulas and the way that they protect the immune system.

  • VitaPost Immune Support
  • Mushroom Defense
  • VitaPost Immune Complex
  • Zenith Labs Nano C
  • Epishield Plus
  • Advanced Bionutritionals Resistol
  • Organixx 7M
  • BioShield MD
  • VitaPost Turmeric & Ginger
  • Immuno Defense 4x
  • Doctor G’s Naturals Q-ION Immune Defense
  • PhyTage Labs Immunity 911
  • Immunity Formulas Immune Support

VitaPost Immune Support

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VitaPost’s Immune Support allows consumers to take advantage of the benefits that certain botanical extracts have to offer. All of the ingredients included are helpful to the immune system in some way, though the creators don’t just stick with the traditional ingredients. Green tea, vitamin C, quercetin, vitamin E, and arabinogalactan are just a few of the ingredients that users get with this remedy.

Users also get the benefit of paying little for one bottle – less than $14.

Mushroom Defense

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Mushroom Defense takes on the natural support that mushrooms provide to the immune system. Studies show that they can reduce the risk of physical and mental fatigue, helping consumers to improve their memory as well. Ultimately, the creators behind this formula focus particularly on the way that Mushroom Defense can help consumers with their viral and bacterial infections as they increase energy levels.

This formula offers up to 67 days to test out the product with its comprehensive refund policy. However, users can rely on many extracts that they don’t get from other products. Some of the mushrooms included are lion’s mane, turkey tail, chaga, maitake, and Agaricus Blazei, though there are many more mushrooms used. This complex is for anyone that wants to see what mushrooms can do for the user. To get one bottle, the total cost is $59.99.

VitaPost Immune Complex

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Even though VitaPost has already been featured once, there’s a second formula on this list that easily makes a big difference in the user’s health – Immune Complex. This formula has many of the same benefits that users get from the Immune Support product listed earlier in this remedy. However, users get a much different collection of ingredients, including probiotics, elderberry, and echinacea.

Probiotics are a necessary aspect of the health of the gut, which is directly associated with the immune system. They reduce the toxic bacteria that can build up in the gut and cause the user to become sicker than the average person. Up to 70% of the immune system relies on the health of the gut and nourishing this part of the body is crucial to keeping it healthy. To get these benefits, users will only have to pay $11.95 for one bottle of the capsules.

Zenith Labs Nano C

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The formula from Zenith Labs – which is called Nano C – provides users with an adequate dose of vitamin C. However, vitamin C is found on nearly every single ingredient list for these supplements because of the crucial role that it plays in the immune system. The bioavailability of vitamin C in Nano C is compressed into a tincture, allowing users to take a few drops a day to make a difference.

The smaller molecules of vitamin C make it easier to enter the bloodstream and work with the immune system. By entering the bloodstream faster, users will start to feel better about their body a lot faster, ensuring that users can recover quickly from infections involving viruses or bacteria. To purchase a bottle of this product, users will have to pay a bit more than others at $49.

Epishield Plus

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Simple Promise’s Epishield Plus provides users with a boost for their immune system, though the users are told that it only takes about two hours to give the boost that they are promised. Many of the ingredients are the same as what users already get from other formulas on the list, like vitamin C, mushroom extract, and vitamin D. However, the use of fermented yeast is rather unique. This variation of fermented yeast is believed to help the user to improve the health of their immune system.

Even though one bottle only costs $49 on the website, consumers may find that it is difficult to purchase this product as it always seems to be out of stock.

Advanced Bionutritionals Resistol

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Advanced Bionutritionals Resistol provides users with five different herbs that can help the immune system to thrive. Those herbs include Andrographis, licorice, Eleuthera, prickly chaff flower, and Platycodon. All of these ingredients can be backed up by scientific evidence to show the way that they support the immune system.

Even though this formula does not include vitamin C, the many herbs and plant extracts provide users with more support than they would typically expect from this type of formula. Plus, each bottle only costs $29.95.

Organixx 7M

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Organixx 7M focuses on helping users with mushroom extracts and other ingredients that can positively impact the immune system. Some of the mushrooms that users will find in this formula include maitake, Reishi, and shiitake, which are the most common ingredients to use in mushroom blends today. They all offer beta-glucans that reduce inflammation and purge the body of toxins.

Users will also get Cordyceps, lion’s mane, and Turkey tail extracts to further support the immune system. They also improve the user’s digestion and protect the body from dealing with common aches and pains. One bottle is currently priced at $55.

BioShield MD

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BioShield MD allows users to take advantage of the immunity boost that their formula provides, thanks to the formulation that was created by Dr. Mark Rosenberg of Sun Coast Sciences. It is the first formula on this list that has the support of a doctor that was used in the creation of the remedy. Along with the boost to the immune system, users will experience more energy, fewer issues with joint pain, and improved mental health. All of the ingredients were chosen for how easily they are used within the bloodstream, and they are all backed up by scientific evidence.

The ingredients of this formula include curcumin, resveratrol, quercetin, tart cherry extract, green tea extract, and other remedies. The formula has tons of antioxidants and flavonoids that help the immune system to thrive, all found in one bottle for $49.95.

VitaPost Turmeric & Ginger

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VitaPost manages to secure a third spot on the list with their Turmeric & Ginger blend. Along with the obvious use of turmeric and ginger, this formula also includes Bioperine, which makes these formulas much more bioavailable within the body. The purpose of combining these ingredients is to reduce inflammation and promote better joint health as they improve immunity. Users get 500 mg of turmeric and 100 mg of ginger and every single dose, and the bottle only costs $23.95.

Immuno Defense 4x

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Immuno Defense 4x is a product from JayLab Pro, and it only uses four ingredients to get the desired effects. Those four ingredients include EpiCor, quercetin, bromelain, and vitamin D3, though users will get 500 mg of the first two ingredients each while bromelain only accounts for 150 mg. even though this formula has as much support as possible, it is the only other remedy that uses dried yeast extract. One bottle is priced at $44.95.

Doctor G’s Naturals Q-ION Immune Defense

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Doctor G’s Q-Ion Immune Defense thrives on the claim that it is doctor approved, which means there has been at least one medical professional there has agreed that the supplement supports immunity. The medical professional in question is board-certified physician Dr. John Gordon, who uses green tea extract, zinc, quercetin, and bromelain to make a profound impact.

The remedy is incredibly helpful for inflammation, and it can protect the body from viral activity and other pathogens that can be detrimental to the user’s health. However, it is one of the more expensive products on this list at $79.95.

PhyTage Labs Immunity 911

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Immunity 911 is one of the latest products from PhytAge Labs, using strong ingredients to protect the body from any kind of infection from the start. It offers Graviola leaf extract, red raspberry extract, and green tea leaf extract, though they are all combined in a proprietary blend. Even with the lack of transparency on the label, it is clear that this formula delivers many extracts that are known for the benefits that they offer the immune system.

With added mushroom extracts, superfruits, and herbs, users will be able to purchase a bottle for $69.95.

Immunity Formulas Immune Support

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Immunity Formulas Immune Support might be the last remedy on the list, but it helps to build up the natural defenses against viruses. It also supports the body’s immunity, using therapeutic grade essential oils. It can be used in a diffuser, providing purification and disinfection to the air around the user.

Some of the essential oils that consumers will find in this formula include lemon, oregano, peppermint, cinnamon, and turmeric. Consumers will be surprised to find that it can also be applied to the skin directly, allowing the body to fully absorb this formula. The total cost of 1 bottle is $64.99.

How the Rankings Were Decided

Every company that creates an immunity-boosting supplement claims that it can help the body to improve its defenses. The right product will use effective and proven ingredients, while others may have strange herbal extracts that don’t have much scientific evidence to back it up. To separate the quality products from the less effective remedies, there were certain criteria that each settlement had to meet.

To learn more about each supplement brand on this extensive list, you may visit the product official website by following the links below:

Contains scientifically proven ingredients

Ingredients like probiotics, vitamin D, and zinc are just a few of the substances that were prioritized over untested herbal extracts. The ingredients used in the supplements above had to be provable in the benefits that they offer, even if the testing was based on third-party research.

Correct dosages

As important as the right ingredient blends would be, it was even more important to ensure that each of these ingredients was used within the right dosage amount. The dosages had to be powerful, but they also could not exceed the recommended amount that is dictated by the FDA.

Genuine health benefits

By law, supplement companies are prohibited from claiming that their products can cure diseases or even improve the user’s health, according to the FDA regulations. Instead, the most that they can do is claim to support health, and there are even companies that have done away with the use of terms like “booster” to fall in line with these laws. Immunity supplements that claim that they can cure disease or prevent the contagious germs associated with COVID-19 were instantly dismissed, never to find a place on this list.

Manufacturing location

Due to the regulations in the United States, this list prioritized formulas that were developed with the country. Some companies seek out ways to reduce their costs by shipping ingredients internationally where they may not be as high in quality. The brands that earned a spot on this list did anything that they could to be seen as reliable in the eyes of consumers, including developing their product within a facility that follows FDA regulations. While supplements cannot technically be approved by the FDA, the decision to produce them in this type of environment garners trust between the brand and its customers.

Staffing of a Medical Advisory Board

Companies that use a Medical Advisory Board often get tips and other guidance from legitimate doctors, allowing them to create a more complete formula. The medical expertise that is available to these companies insure that they offer a more reliable immunity blend. Companies that do not consult with medical professionals often are unable to provide the same quality to consumers.

The reputation of the brand

As important as quality might be, there are far too many bad players in the supplement industry today that simply want to cash in on a trend. Considering the widespread COVID-19 pandemic, the ability to increase the health of the immune system has been an excellent way for these bad actors to make money. The brands preferred for this list had to have an established reputation amongst their customers for their honesty and effectiveness.

Ingredient transparency

While the use of ingredients that may be less common wasn’t a deal-breaker, these companies had to be honest about the product’s recipe. Proprietary blends leave far too much room to conceal the actual amounts of each ingredient used. While proprietary blends were not completely disqualified from this list, the formulas they earned a higher ranking had reputable and transparent sources for their ingredients.

High quality with a good price

Improving the immune system comes at a cost, but it doesn’t have to be a high one. Some consumers prefer to spend only $10 on the supplement to support their immune system, while others may want to spend well over $100. No matter what the price tag was, each of the supplements on this list offered incredible value for their cost.

Side Effects of Taking an Immunity Booster

When someone takes an immunity-boosting supplement, following the directions is the key to avoiding any type of side effect. The majority of the ingredients used in these supplements are natural and safe for the body, so the risk of experiencing any adverse effect is rather low in most circumstances. However, these companies can’t account for the unpredictable reactions in the body when consumers do not use the products correctly.

Individuals that are currently using any type of medication may want to speak with their doctor before integrating a supplement into their routine, regardless of what the supplement does. Even without taking medication, some consumers experience bloating or indigestion when they take a capsule since these capsules can be a little difficult for the digestive system to process.

Every supplement company must abide by certain guidelines when using these ingredients. These doses are “Generally Recognized as Safe” by the FDA, and users will not experience an adverse reaction under these circumstances.

Scientific Evidence Behind Immunity-Boosting Formulas

With the right use of fruits, vitamins, minerals, and other extracts, it is possible to support immune function in the body. These ingredients need to be incorporated into a daily diet to help with the defense against illness, disease, and the damage that aging causes. The immune system needs to be cared for properly, and immunity-boosting supplements have proven to be an incredibly helpful remedy for this purpose.

One of the easiest ways to promote a healthy immune system is to maintain a balanced diet and incorporate positive lifestyle habits. Consumers that prioritize hydration and get enough sleep each night can see an incredible impact on the immune system. If the individual eats poorly or follows bad habits in their daily life, the body is simply unable to defend itself.

A weakened immune system can be the result of too much sugar in the diet, but it can also come from excessive alcohol and cigarette use, dehydration, obesity, and stress. Even abstaining from exercise can be damaging to the immune system.

One of the most popular ingredients to include in an immunity-boosting supplement is vitamin C, providing antioxidants in a way that many other vitamins cannot. The National Institutes of Health states that it is necessary to include vitamin C to synthesize collagen and many other neurotransmitters. It also helps to create connective tissue and promote wound healing. For some people, having enough vitamin C can mean the difference in the development of certain cancers, protecting them from detrimental future diseases.

Vitamin D is also incredibly important, helping the user to maintain proper immune function and to protect against autoimmunity. Individuals that get enough vitamin D often reduce their risk of infection, even when it comes to the flu. It can treat conditions as severe as tuberculosis, even without antibiotics in certain situations. Most of the time, consumers can get vitamin D from milk and other food sources. Vitamin D3, however, can be attained by spending some time in the sun, allowing the body to convert it into a usable vitamin D.

Protein is a necessary nutrient to keep the immune system functioning properly, but the majority of the products on this list don’t contain any. Protein is composed of amino acids, which can be used as fuel to keep the immune system going. Fish, poultry, eggs, soy products, and nuts are just a few examples of protein sources. Protein helps users to improve their gut, keeping up the immunity of the intestinal cells.

One of the most common remedies to boost the immune system is to take a zinc supplement. This mineral works much like vitamin D does and being deficient in it puts the user at great risk of poor immune function. Individuals that have less zinc in their body are often prone to diseases that come from infection. By using zinc, users will find that it has an incredible anti-inflammatory effect, and it delivers necessary antioxidants that can prevent the body from succumbing to immune dysfunction. Some of the common sources of zinc include meat, whole grains, oysters, and nuts.

Probiotics are perhaps one of the most popular types of supplements on the market today. Since approximately 80% of the immunity cells are found within the gut, it is more important than ever to take care of this area. Ignoring the health of the gut could cause the immune system to greatly suffer, especially considering the many diseases and viral infections they can be prevented with the right balance of bacteria. Some studies suggest that allergies can be treated or even prevented with the habitual use of probiotics.

Most people outside of Europe are not aware of the benefits that elderberry offers, but many people use it for the medicinal and health benefits it has been found to provide. Sometimes, consumers use it as a home remedy to deal with symptoms associated with the cold or flu, though some doctors recommend using it to specifically boost the health of the immune system.

Much like elderberry and any other ingredient listed above, echinacea has been used medicinally and can support the health of the immune system. Even the short-term use of it can drastically reduce how severe a respiratory infection can be. For the best timing, this ingredient should be used right when symptoms begin, since it is significantly less helpful if taken days later.

Ginger is also becoming a rather popular ingredient to include in immunity-boosting supplements. It has already been studied extensively for the antibacterial and antiviral benefits that it provides, thanks to the antioxidants that come from gingerol. It supports the body in a similar weight that garlic does, though there is extensively more research to back it up. Some researchers even suggest that it could be used as an immunity superfood.

With the way that it balances inflammation, it should come as no surprise that turmeric plays a major role in immunity as well. It is a rich source of compounds like curcumin that reduce inflammation, though it also provides antioxidants and other compounds that activate certain areas of the immunity cells. To get the most out of turmeric, many researchers find that the body can absorb it more effectively when it is paired with what is black pepper extract.

Finding ways to protect the body from illness has constantly been a priority among scientists, which is why there is so much evidence to support which ingredients help the immune system most greatly.

FAQs About Immunity Boosters

Q: How does immunity help consumers?

A: Every human body hasn’t immune system, and the role of the immune system is to keep out harmful materials that could cause damage. When something threatens the immune system, there are multiple layers of response. They are the first line of defense against many pathogens that attempt to enter the body. When the immune system works in the way that it is supposed to, it eliminates the invaders to protect the individual from harm.

Q: What are T cells?

A: Many immunity-boosting supplements will claim that they can increase or target T cells. These cells are meant to fight infection by activating B cells, releasing the antibodies they can kill off infected cells. Some T cells also destroy the infected cells without releasing any antibodies at all.

Q: What are antibodies?

A: Antibodies are produced by the immune system as proteins, fighting off infections and disease. They are a necessary part of the immune system.

Q: What are the best vitamins to increase immunity?

A: Many vitamins contribute to a stronger immune system, including vitamin D, vitamin C, and vitamin E. Scientific studies back up the way that these vitamins can change and support the immune system, and it is extremely dangerous to be deficient in any of them.

Q: What does innate immunity mean?

A: Innate immunity is a term that describes the first line of defense when foreign substances attempt to enter the body. Skin, mucus, and stomach acid are all examples of innate immunity. Some supplements attempt to target this response as well.

Q: What is the difference between innate immunity and adaptive/acquired immunity?

A: While innate immunity focuses on the ability to protect the body from new invaders, adaptive or acquired immunity comes in when the immune system has already familiarized itself with a pathogen. This part of the immune system is regulated by the lymph nodes, bone marrow, spleen, and thymus, which all release the antibodies that they create when the pathogen threat is detected.

Q: What foods can support immunity easily?

A: Foods like red grapes, turmeric, elderberry, ginger, dark chocolate, and leafy greens all help to support the function of the immune system.

Q: What foods might hurt the immune system?

A: Unfortunately, consumers destroy their immune system every day with added sugars, foods that contain artificial trans fats, refined carbohydrates, fast food, and junk food. Processed meat is also incredibly damaging to the immune system, as is white bread, pasta, and many baked goods.

Q: Will losing weight help consumers to improve their immune systems?

A: Possibly. Researchers have found that individuals who maintain a healthy weight tend to have a stronger immune system than individuals who struggle with obesity.

Q: How can consumers increase the strength of their immune system?

A: Maintaining a healthy lifestyle and eating healthy foods in a balanced diet has an incredible impact on the immune system. Exercise is also helpful to individuals that want to boost immunity.

Q: What are some bad habits that can destroy the immune system?

A: Smoking cigarettes, eating a diet that is full of unhealthy foods, consuming excessive amounts of alcohol, maintaining poor sleep habits, and finding new relief from stress can all impact immunity. This is not a complete list of all the bad habits that can change the immune system, but they are some examples of what not to do.

Q: Why is gut health such an important part of immunity?

A: Up to 80% of every cell in the immune system can be traced back to the gut. The gut has a major role in immunity, which is why so many formulas have included probiotics in their ingredients.

Q: Does the immune system suffer as individuals get older?

A: Yes. Age can cause the immune function to decrease, which is why it is so easy for older individuals to become ill. Still, it is possible to improve lifestyle habits to make a difference in the immune system, regardless of age.

Q: Is it possible for an immunity supplement to help?

A: Yes. In fact, the majority of supplements on the market today can improve immunity without directly offering it as a benefit. Still, the Food and Drug Administration prohibits companies from claiming that their products can cure any disease, improve health, or improve immunity.

Q: Is it helpful or harmful to the immune system to exercise?

A: Everything is better in moderation. Maintaining moderate exercise can positively impact the user’s immunity. Most people who are at a healthy weight tend to have a stronger immune system than individuals who don’t. Still, putting the body through strenuous exercise regularly can damage the immune system if recovery is not a priority.

Q: Will users be able to improve their immune system with vitamin C?

A: Yes. Vitamin C provides the body with antioxidants, eliminating the free radicals that can cause disease or illness. While it doesn’t prevent individuals from succumbing to a respiratory illness or the common cold, it can help users reduce how long they suffer from these illnesses.

Q: Does vitamin D improve immunity?

A: Yes. There are many different ways that the immune system benefits from using vitamin D. In fact if an individual does not get enough vitamin D, their immune system will not function as well as it should.

Q: Can users boost immunity with echinacea?

A: Yes. One of the reasons that echinacea has been part of traditional medicine is for the way that it improves immunity. When dealing with the beginning of a cold or flu, some research has shown that it helps to fight those germs. However, studies have not been consistently clear regarding this effect.

Q: How does zinc help immunity?

A: Zinc is a necessary mineral for the body, and the immune system will not thrive without it. Anyone who takes zinc at the beginning of a cold may be able to reduce how long the symptoms last.

Q: Can users improve the immune system with probiotics?

A: Yes. The purpose of probiotics is to support the health of the gut. Since the gut has approximately 80% of the immune cells, keeping it healthy is one way to trigger improved immunity. Though there is still a lot of research to be done, one study indicates that using probiotics can reduce how long a respiratory infection lasts.

Q: Will elderberry promote better immunity?

A: Yes. It is primarily used as a folk remedy in Europe, but researchers have found that elderberry is great for the immune system. It has a high amount of vitamin C, and it may be able to reduce the amount of time that consumers suffer from a cold.

Q: Will taking turmeric promote a better immune system?

A: Yes. Turmeric also has an antioxidant effect, reducing the oxidation that can lead to illness. Turmeric also reduces inflammation, which can greatly boost immunity with regular use.

Q: How does stress impact the immune system?

A: Stress can make it more difficult for the body to defend itself against illness. When the body is stressed, it naturally releases cortisol, adrenaline, and other hormones as a way to cope with the trigger. Cortisol can help with the inflammation that occurs in the body, but constant stress can cause a greater risk of health issues to arise.

Q: Should users increase their immunity by exposing themselves to more germs?

A: Germs are a necessary part of staying healthy, and the immune system is capable of adapting when it comes against a foreign pathogen. As it fights the pathogen, the immune system creates a memory of the way that it was able to overcome it. In the event that the body ever encounters these germs again, it can easily heal or protect itself.

Q: If an individual has allergies, is this a sign that their immune system is weak?

A: Allergies are simply a reaction from the immune system that they have mistaken as a pathogen. Certain types of food or even pollen can trigger this mistaken response, which is the reason that some people experience allergy symptoms.

Q: What is an autoimmune disorder?

A: Autoimmune disorders cause the body to attack itself without cause. Essentially, the body starts to attack its tissues, believing that it is a foreign pathogen instead of the existing body. Some of the most common autoimmune disorders include psoriasis, lupus, and rheumatoid arthritis.

Q: How will a vaccine impact the immune system?

A: When someone is vaccinated, their immune system learns to produce the antibodies against the pathogen that they are designed to protect against. They do not infect the individual with the illness, but they allow the body to learn the proper defense against that disease. Many vaccines will use some component of the pathogen, allowing the immune system to learn the defense it needs to have.

Q: Will garlic help users to improve immunity?

A: Studies seem to be mixed on the effect of garlic on the body. While some studies support the immunity benefits, others have found no correlation between garlic and wellness. The main reason that garlic seems to be tied to immunity is that it naturally offers antiviral and antimicrobial effects as the result of allicin sativum.

Best Immunity Boosters of 2021 Final Thoughts

Every immunity booster provides users with the vitamins, minerals, and extracts that can help the body to effectively handle sickness. Ingredients like vitamin C, zinc, and echinacea are just a few of the substances that are known to promote better immunity. With the right match, consumers can effectively defend themselves against infectious illnesses and diseases. All of the formulas on this list provide users with different ways to promote a strong immune system, thanks to elaborate research and strict criteria.

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Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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